The Clear Skin Project Blog

Acne Treatment and the Transgender Community

Some new insight in a recent article in Dermatology News explains how iPLEDGE cimagetempalte_6lassification for transgender patients can be challenging. Some of the patient considerations include changing hormone levels and childbearing potential.

Patients who wish to take isotretinoin, one of the most common acne treatments, are subject to the requirements of the iPLEDGE Program, a federally mandated computer-based risk management program. Based on gender, it is designed to eliminate fetal exposure by isotretinoin use. The program strives to ensure that no female patient starts isotretinoin therapy if pregnant and no female patient on isotretinoin therapy becomes pregnant.

At the annual meeting of the American Academy of Dermatology, Dr. Brian Ginsburg, a New York–based dermatologist, recommended modifying patient intake forms to allow the individual to self-identify gender and respecting the use of correct pronouns preferred by patients. Additionally, having “honest conversation” with patients who were previously registered on iPLEDGE regarding their gender classification is important.


Want to learn more? The full article by Elizabeth Mechcatie can be found here:

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Pros & Cons of Using Antibiotics For Acne Treatment

Causes of Acne
Causes of Acne

While once thought to be successful acne treatments solely for reducing P. acnes bacteria, the anti-inflammatory properties of antibiotics have proven to be much more effective. In a recent article in The Conversation, Dr. Adam Friedman, Associate Professor of Dermatology at George Washington University, explains that antibiotics, such as doxycycline and minocycline, inhibit the production of pro-inflammatory signaling molecules that drive the inflammation behind acne.

Despite their success reducing inflammation, antibiotics must be used with caution. Antibiotics have a history of being prescribed at higher doses and longer durations than necessary to kill P. acnes and reduce inflammation, leading to the development of antibiotic resistant bacteria. Dr. Friedman mentions that sub-antibacterial doses of antibiotics (doses that are too low to kill bacteria) still have anti-inflammatory effects without killing good bacteria or causing resistance in pathogenic bacteria. He also references professional treatment guidelines which always recommend combining antibiotics with nonantibiotic topical treatments such as benzoyl peroxide or retinoids.

Future treatments that are currently in trial will focus on agents that kill P. acnes or reduce inflammation without leading to microbial resistance. Promising solutions include using synthetic antimicrobial peptides to destroy P. acnes or using nitric oxide to both kill P. acnes and reduce inflammation.Roblox Robux Hack 2017

In the meantime, Dr. Friedman recommends that acne patients work closely with their dermatologists to manage the proper dosing and duration of antibiotic treatments.

For more detailed information, check out the full article:

Let’s Talk Lasers

Face treatmentLasers have come a long way in a short amount of time when talking about acne treatment.  There is virtually a specific laser for every need.  Often a patient will need to be treated by more than one laser depending on the types of acne or rosacea lesions present.  Lasers can be used to treat acne itself:

  • to eradicate the pimples themselves
  • to treat the consequences of acne

Different types of laser treatments include:

  • Dye lasers – used to treat the red lesions (or red remnants of lesions) of acne and for the background redness of rosacea
  • Blue light and light with a photosensitizer (photodynamic therapy) – used to treat acne itself
  • Fraxel lasers and fillers can be used to lessen acne scars

Check with your dermatologist on what laser treatment might work best for you!